Washed cartridges enter the sterilizing and depyrogenating tunnel through the infeed section : – 

• Washed cartridges are automatically introduced into the sterilizing and depyrogenating tunnel through the dedicated infeed section.
• The cartridges are accurately positioned and conveyed into the tunnel to maintain a smooth and continuous process flow.
• Controlled handling helps prevent physical damage and unnecessary contact with the cleaned cartridge surfaces.
• The infeed conveyor ensures consistent spacing and proper orientation of cartridges throughout the process.
• This stage provides a controlled transition from the cartridge washing machine to the sterilization and depyrogenation process.

Cartridges pass through controlled heating zones at high temperature : –  

• The cartridges pass through multiple controlled heating zones maintained at predetermined high temperatures.
• Hot, HEPA-filtered air is circulated uniformly around the cartridges to provide effective and consistent thermal treatment.
• Temperature, airflow, and exposure time are carefully controlled throughout the heating process.
• Multiple heating zones allow the required thermal profile to be achieved gradually and consistently.
• Uniform heat distribution helps ensure reliable treatment of the entire cartridge surface.

The process sterilizes the cartridges and removes pyrogens :- 

• During the high-temperature treatment, microorganisms present on the cartridge surfaces are effectively inactivated.
• The controlled thermal process also helps reduce bacterial endotoxins, commonly known as pyrogens.
• Precise control of temperature and exposure time supports consistent sterilization and depyrogenation performance.
• The process helps prepare the cartridges for subsequent aseptic filling and closing operations.
• This critical stage supports the required microbiological quality and cleanliness of the cartridges.

Sterile cartridges are cooled under controlled conditions and transferred to the filling area :- 

• After completing the high-temperature treatment, the sterile cartridges enter the controlled cooling section of the tunnel.
• Filtered air is used to gradually reduce the cartridge temperature while maintaining a controlled processing environment.
• The cartridges remain protected from external contamination during the cooling and transfer process.
• Once cooled to the required temperature, the cartridges are automatically conveyed toward the filling area.
• The controlled transfer maintains cartridge cleanliness and supports continuous aseptic pharmaceutical production.