1. Empty Tube Infeed

• Empty blood collection tubes are automatically transferred from the upstream conveyor to the dosing machine.
• Tubes are indexed into precision holders using a servo-driven indexing system.
• Sensors detect tube presence and ensure proper positioning before dosing begins.

2. Tube Positioning

• Each tube is accurately positioned beneath the dosing nozzles.
• The indexing mechanism ensures precise alignment for uniform filling.
• Tube presence sensors prevent dosing into empty positions.

3. Sodium Citrate Solution Feeding

• The Sodium Citrate solution is stored in a GMP-compliant SS316L stainless steel storage tank equipped with:
  • Low-level sensor
  • Agitator (if required)
  • Level indicator
  • Sanitary piping
  
  
• The solution is continuously supplied to the dosing manifold through hygienic tubing.

4. Precision Liquid Dosing

• Servo-controlled piston pumps or precision metering pumps dispense the programmed volume of Sodium Citrate into each tube.
• Multiple dosing heads allow simultaneous filling of several tubes, increasing production efficiency.
• Filling parameters are adjustable through the HMI to accommodate different tube sizes and additive volumes.
• The dosing nozzles are equipped with anti-drip and suck-back mechanisms to prevent dripping and cross-contamination.

5. Dose Verification (Optional)

• Integrated sensors or weighing systems verify:
  • Additive presence
  • Correct dosing volume
  • Filling consistency


• Any abnormal dosing condition triggers an alarm and the affected tube is automatically rejected.

6. Tube Discharge

• After successful dosing, the tubes are automatically transferred to the downstream conveyor.
• The dosed tubes proceed to subsequent processes such as drying (if required), stoppering, vacuuming, capping, labeling, and packaging.